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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BLM All Species: 15.15
Human Site: T843 Identified Species: 25.64
UniProt: P54132 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54132 NP_000048.1 1417 159000 T843 R V Q K D I L T Q L K I L R P
Chimpanzee Pan troglodytes XP_510594 1417 158822 T843 R V Q K D I L T Q L K I L R P
Rhesus Macaque Macaca mulatta XP_001097543 1416 158885 T842 R V Q K D I L T Q L K I L R P
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88700 1416 158347 T851 R V Q K D I L T Q L K I L R P
Rat Rattus norvegicus Q6AYJ1 621 69624 H81 P W S G K V K H V L R D V F K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515695 791 89186 R251 F D C L S W I R K H H P Y D S
Chicken Gallus gallus Q9I920 1142 126164 K602 D V L P K K P K K V A M D C L
Frog Xenopus laevis Q9DEY9 1364 152305 N795 R V K K D I L N Q L K M T K P
Zebra Danio Brachydanio rerio XP_701357 1261 139417 T721 A C V S A G V T V V I S P L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGI8 1487 166060 A913 R V R L D I L A Q L N L K N C
Honey Bee Apis mellifera XP_396209 961 109321 T421 D C F I L M P T G G G K S L C
Nematode Worm Caenorhab. elegans O18017 988 110641 L448 R D N L K Y D L I P K A A R S
Sea Urchin Strong. purpuratus XP_001175892 1394 152920 R844 L I Q D Q V Q R L V S L E I Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35187 1447 163819 H856 Q V R M D I I H N L E L K E P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 96.1 N.A. N.A. 76.9 21.2 N.A. 46.3 47.9 50.8 41.6 N.A. 27.8 30.9 26.5 31.5
Protein Similarity: 100 99.2 97.7 N.A. N.A. 85.2 30.9 N.A. 50.1 60.7 66.6 54 N.A. 47 47.1 40.2 47.6
P-Site Identity: 100 100 100 N.A. N.A. 100 6.6 N.A. 0 6.6 66.6 6.6 N.A. 46.6 6.6 20 6.6
P-Site Similarity: 100 100 100 N.A. N.A. 100 26.6 N.A. 13.3 26.6 86.6 20 N.A. 60 13.3 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 8 0 0 8 0 0 8 8 8 0 0 % A
% Cys: 0 15 8 0 0 0 0 0 0 0 0 0 0 8 15 % C
% Asp: 15 15 0 8 50 0 8 0 0 0 0 8 8 8 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 8 0 8 8 0 % E
% Phe: 8 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 8 0 8 0 0 8 8 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 15 0 8 8 0 0 0 0 % H
% Ile: 0 8 0 8 0 50 15 0 8 0 8 29 0 8 0 % I
% Lys: 0 0 8 36 22 8 8 8 15 0 43 8 15 8 8 % K
% Leu: 8 0 8 22 8 0 43 8 8 58 0 22 29 15 8 % L
% Met: 0 0 0 8 0 8 0 0 0 0 0 15 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 8 8 0 8 0 0 8 0 % N
% Pro: 8 0 0 8 0 0 15 0 0 8 0 8 8 0 43 % P
% Gln: 8 0 36 0 8 0 8 0 43 0 0 0 0 0 8 % Q
% Arg: 50 0 15 0 0 0 0 15 0 0 8 0 0 36 8 % R
% Ser: 0 0 8 8 8 0 0 0 0 0 8 8 8 0 15 % S
% Thr: 0 0 0 0 0 0 0 43 0 0 0 0 8 0 0 % T
% Val: 0 58 8 0 0 15 8 0 15 22 0 0 8 0 0 % V
% Trp: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _